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The relative abundance of Erysipelatoclostridium was increased in vehicle-treated mice that underwent the WD to LD switch (WD/LD-V) relative to the two control groups (LD/LD-V and WD/WD-V) but was not increased in 5A-1MQ-treated mice that underwent the same diet switch (WD/LD-T)

For DNA repair genes, GHK was primarily stimulatory (47 genes up, 5 genes down), with particularly strong effects on genes like XRCC5 (369% increase) and BRCA2 (189% increase)both critical for maintaining genomic stability

Kong, Nrf2 plays an important role in coordinated regulation of Phase II drug metabolism enzymes and Phase III drug transporters

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